Detectives from the Serious Collision Investigation Unit (SCIU) are appealing for information after a motorcyclist was left seriously injured.
Police were called on Wednesday, 6 December at 21:20 hours to a report of a car in collision with a motorcycle in Glen Road junction with Prince Regent Lane, E13.
Officers attended along with the London Ambulance Service and found the motorcyclist, a 33-year-old man with a serious head injury.
He has been taken to an east London hospital and his injuries are described as life-threatening.
The car stopped at the scene, the driver has not been arrested and is assisting police with their inquiries.
Any witnesses or anyone with information should contact the SCIU on 0208 5974874 or call police on 101.