Detectives are appealing for witnesses following a serious road traffic collision in Tower Hamlets.
Police were called just after 01:00hrs on Thursday, 12 October to a collision between a motorcycle and a pedestrian on Whitechapel Road, near the Royal London Hospital.
Officers and the London Ambulance Service attended.
A woman, aged in her 30s, who was a pillion passenger on the motorbike, was taken to a east London hospital where she remains in a critical condition.
Next of kin have not been informed.
The rider of the motorcycle stopped at the scene and is assisting police with their enquiries.
The motorcyclist and a pedestrian were also injured in the collision; neither injury is described as life-threatening.
Anyone who witnessed, or anyone with information about, the collision is asked to call investigating officers from the Roads and Transport Policing Command on 020 8497 4874 or contact via Twitter @MetCC
To give information anonymously contact Crimestoppers on 0800 555 111 or online at crimestoppers-uk.org
No arrests have been made. Enquiries are ongoing.